Ying Gibbens

Research Interests:

Insect metamorphosis is triggered by a high pulse of 20E, the active form of ecdysone which is produced from the prothoracic gland (PG). However how this 20E pulse is generated remains poorly understood. We found that activin signaling in the PG is required for the production of ecdysone. My project therefore investigates the molecular mechanism by which Activin signaling regulates ecdysone synthesis.

Publications:

(Names in bold are members of the O'Connor lab)

1). Takaesu, N.T., Hyman-Walsh, C., Ye, Y., Wisotzkey, R.G., Stinchfield, M.J., O’Connor, M.B., Wotton, D. and Newfeld, S.J. (2006). dSno Facilitates Baboon Signaling in the Drosophila Brain by Switching the Affinity of Medea Away From Mad and Toward dSmad2. Genetics 174, 1299–1313.

2). Ye, Y., Ho, J.W., Chen, Z.Y. and Wang, J. (2005). Analysis of theanine in tea leaves by HPLC with fluorescence detection. J. Liq. Chromatogr. & Rel. Techno. 28, 727 – 737.