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email: oconn033@umn.edu
I work on a variety of projects as needed. Currently I am making a reagent, which could be utilized in the ecdysone/developmental timing project. Other tools I am developing could prove useful in modeling the early axis. In addition to having small research projects, I manage our fly stock database and organization of the lab in general.
(Names in bold are members of the O' Connor lab)
Ono H, Rewitz KF, Shinoda T, Itoyama K, Petryk A, Rybczynski R, Jarcho M, Warren JT, Marques G, Shimell MJ, Gilbert LI, O'Connor MB. 2006 Oct Spook and Spookier code for stage-specific components of the ecdysone biosynthetic pathway in Diptera. Dev Biol 15;298(2):555-70. Epub
McBrayer, Z.*, Ono, H.*, Shimell, MJ*, Parvy, J.-P., Beckstead, R.B., Warren, J.T., Thummel, C.S., Dauphin-Villemant, C., Gilbert, L.I., and O’Connor, M.B. (2007) Prothoracicotropic hormone regulates developmental timing and body size in Drosophila. Dev. Cell 13: 857-871
Warren JT, Yerushalmi Y, Shimell MJ, O'Connor MB, Restifo LL, Gilbert LI (2006). Discrete pulses of molting hormone, 20-hydroxyecdysone, during late larval development of Drosophila melanogaster: correlations with changes in gene activity. Dev. Dyn. 235, 315-26.
Marques G, Bao H, Haerry TE, Shimell MJ, Duchek P, Zhang B, O'Connor MB (2002). The Drosophila BMP type II receptor Wishful Thinking regulates neuromuscular synapse morphology and function. Neuron 33, 529-43.
Shimell MJ, Peterson AJ, Burr J, Simon JA, O'Connor MB (2000). Functional analysis of repressor binding sites in the iab-2 regulatory region of the abdominal-A homeotic gene. Dev. Biol. 218, 38-52.
Brummel T, Abdollah S, Haerry TE, Shimell MJ, Merriam J, Raftery L, Wrana JL, O'Connor MB (1999). The Drosophila activin receptor baboon signals through dSmad2 and controls cell proliferation but not patterning during larval development. Genes Dev. 13, 98-111.
Marques G, Musacchio M, Shimell MJ, Wunnenberg-Stapleton K, Cho KW, O'Connor MB (1997). Production of a DPP activity gradient in the early Drosophila embryo through the opposing actions of the SOG and TLD proteins. Cell 91, 417-26.